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HPV Testing: How It Works

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Testing

HPV Testing: How It Works

References UK clinical guidance from the NHS, the British HIV Association (BHIVA), and the British Association for Sexual Health and HIV (BASHH). Last updated: April 2026.

HPV testing in the UK is mainly done as part of cervical screening, where samples are checked for high-risk HPV types before being examined for cell changes. There’s no routine HPV test for men, and home HPV tests are not standard. Understanding how and why HPV testing happens helps you make sense of screening letters and appointments.

Here’s what you need to know.

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Who Gets HPV Tested?

GroupHPV Testing Approach
Women 25-64Part of routine NHS cervical screening
Women with HIVAnnual cervical screening including HPV
MenNo routine HPV testing
Men with HIVSome clinics offer anal HPV screening
MSM at higher riskAnal HPV screening available at some centres

How Cervical Screening Works

Since 2019, NHS cervical screening in England uses HPV as the primary test:

  1. A cell sample is collected from the cervix
  2. The sample is tested for high-risk HPV types
  3. If HPV is found, the same sample is then checked for abnormal cells
  4. Results are sent by letter

What Results Mean

HPV negative

No high-risk HPV detected. No need for further tests. Return to routine screening in 3-5 years (depending on age).

HPV positive, no cell changes

HPV found but no abnormal cells. Usually means re-testing in 12 months.

HPV positive, with cell changes

HPV found and abnormal cells detected. Colposcopy referral for closer examination and possible treatment.

HPV Testing in Men

There is no routine HPV test for men in the UK. Genital warts are diagnosed visually. For MSM at higher risk, some clinics offer anal cytology (anal smear) and HPV screening, particularly for those with HIV.

Home HPV Testing

Home HPV tests exist but aren’t routinely recommended in the UK. The NHS cervical screening programme is the primary pathway for most women. If you have concerns, speak to your GP or sexual health clinic.

HPV Vaccination

Even if HPV testing finds you have the virus, vaccination can still protect against types you haven’t yet encountered. The HPV vaccine is routine for adolescents in UK schools and available free for MSM up to age 45.

Treatment

There’s no drug that cures HPV itself — the immune system usually clears it. Treatment targets the effects:

  • Genital warts — topical creams, cryotherapy, surgery
  • Cell changes — LLETZ procedure or cone biopsy
  • Cancers — standard cancer treatment

Read more: What is HPV? | Cervical screening and HIV | Can HPV clear?

Frequently Asked Questions

Can men be tested for HPV?

Not routinely. Visual diagnosis of warts is standard. Anal screening is available for some at-risk groups.

Do I need HPV testing between smears?

Not usually. Follow your NHS screening schedule unless your clinician advises otherwise.

What if my HPV test is positive?

Most HPV infections clear on their own. Your clinic will advise on follow-up based on whether cell changes are present.

Sources

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