STI Treatments

Fluconazole: Uses, Dosing and Side Effects

treat antifungal
STI Treatments

Fluconazole: Uses, Dosing and Side Effects

References UK clinical guidance from the NHS, the British HIV Association (BHIVA), and the British Association for Sexual Health and HIV (BASHH). Last updated: April 2026.

Fluconazole is an antifungal medication widely used to treat thrush (candidiasis). A single 150mg capsule is the standard treatment for uncomplicated vaginal thrush. It’s available from pharmacies without prescription for mild cases and works by killing the Candida yeast that causes the infection.

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Common Uses

ConditionDose
Vaginal thrushSingle 150mg capsule
Penile thrush150mg capsule
Oral thrush50-100mg daily for 7-14 days
Recurrent thrushWeekly or monthly maintenance

Side Effects

  • Nausea
  • Headache
  • Abdominal discomfort
  • Rarely: liver effects

When to See a Doctor

  • First episode (confirm diagnosis)
  • Pregnancy
  • Recurring infections
  • Symptoms not improving

Read more: Diflucan | What is thrush? | Thrush or STI?

Frequently Asked Questions

Can I buy fluconazole without prescription?

Yes for uncomplicated vaginal thrush.

How fast does it work?

Usually 1-3 days.

Is it safe with HIV medication?

Generally yes — check with your pharmacist.

Sources

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