Testing

Blood Test for Syphilis, Hepatitis B and Hepatitis C

Finger Prick Blood Test For Syphilis, Hepatitis B, and Hepatitis C
Testing

Blood Test for Syphilis, Hepatitis B and Hepatitis C

References UK clinical guidance from the NHS, the British HIV Association (BHIVA), and the British Association for Sexual Health and HIV (BASHH). Last updated: April 2026.

Combined finger-prick blood testing can screen for syphilis, hepatitis B and hepatitis C in one simple sample. These three blood-borne infections can all be silent for years, so testing is the only reliable way to know your status. Modern home kits and NHS services offer this combined panel either as a standalone test or as part of a comprehensive STI screen.

Here’s what’s included.

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What’s Tested

InfectionWhat’s Detected
SyphilisTreponemal antibodies (indicates exposure or active infection)
Hepatitis BSurface antigen (HBsAg) — current infection
Hepatitis CAnti-HCV antibody — past or current exposure

Why These Three Together?

  • All three are blood-borne
  • All three can be silent for years
  • All three are serious but treatable
  • Convenient single sample collection

Who Should Test?

  • Anyone with new sexual partners
  • People who have ever injected drugs
  • Men who have sex with men
  • People from countries with high hepatitis prevalence
  • Those with HIV
  • Sexual contacts of people with these infections
  • People with unexplained liver problems

Window Periods

  • Syphilis — reliable from 3-12 weeks post-exposure
  • Hepatitis B — reliable from 6 weeks to 3 months
  • Hepatitis C — reliable from 6 weeks to 3 months

How to Use a Home Kit

  1. Order or collect a kit
  2. Wash hands and warm them to encourage blood flow
  3. Use the lancet to prick your finger
  4. Collect drops of blood as instructed
  5. Seal and post back to the lab
  6. Receive results by text, email or secure portal

Accuracy

Finger-prick blood tests processed by reputable labs are highly accurate. Sample collection technique matters — follow instructions carefully and ensure you collect enough blood.

What Results Mean

Negative

No detected infection (assuming you tested past the window period).

Positive

Possible infection — confirmation testing needed. The service will contact you with next steps.

Treatment Overview

  • Syphilis — penicillin injection (curative)
  • Hepatitis B — antiviral suppression (long-term)
  • Hepatitis C — direct-acting antivirals (curative in over 95%)

Where to Get Tested

  • NHS sexual health clinic — free
  • Free postal kits in many areas
  • Private services for paid options
  • Liver clinics for hepatitis-specific monitoring

Read more: Hepatitis B and C | Hepatitis C testing | 4 stages of syphilis

Frequently Asked Questions

Is one finger-prick enough for all three tests?

Yes — a small blood sample is enough for combined testing.

Are these tests confidential?

Yes — NHS and reputable private services protect your privacy.

How quickly will I get results?

Usually a few days after the lab receives your sample.

Sources

Have questions? Get tested from home.

Confidential, accurate, and rapid results you can trust.

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